Effects of exercise on the quality of life in breast cancer patients: a systematic review of randomized controlled trials
Xinyan Zhang1 & Yuxiang Li1 & Dongling Liu1. Supportive Care in Cancer 2018
Purpose The purpose of this study was to conduct a systematic review to assess the effect of exercise on the quality of life among people with breast cancer.
Methods We conducted a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.The Cochrane Library, PubMed, EMBASE, Web of Science, CINAHL, and four Chinese data bases were searched for studies published until January 2018. The review included all randomized controlled trials that evaluated the effect of exercise on quality of life compared with that of usual care for people with breast cancer. Two reviewers independently assessed the quality of all the included studies using the Cochrane Handbook for Systematic Reviews of Interventions.
Results In total, 36 studies (3914 participants) met the inclusion criteria. We divided the exercise into three modes: aerobic, resistance, and a combination of aerobic and resistance. All three modes of exercise intervention showed a significant effect on quality of life between groups.
Conclusions Exercise is a safe and effective method of improving the quality of life in patients with breast cancer. In particular, combined training was associated with a significant improvement in quality of life. In future research, more high-quality, multicenter trials evaluating the effect of exercise in breast cancer patients are needed.