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T*
[(Ea)18.5(ch)-233.8(co)19.7(un)20.8(tr)15(y)-237.2(h)0(a)19.7(d)-243(a)-244.2(p)0(r)20.9(i)0(n)20.7(c)0(i)19.6(p)0(a)19.7(l)-243.1(in)20.7(ve)19.7(st)15.1(ig)20.7(at)19.5(or)-232.6(wh)20(o)-243(e)0(n)19.7(s)0(u)21(r)0(e)19.7(d)-243(et)19.6(hi)20.7(ca)18.5(l)]TJ
0 -1.1174 TD
[(ap)13.9(pr)20.9(ov)20.8(al)-297.2(wa)18.8(s)-311.9(o)0(b)20.8(t)0(a)19.5(i)0(n)20.7(e)0(d)19.7(.)-308.7(Ea)18.5(ch)-302.9(co)19.7(un)20.8(tr)20.7(y)-312.1(a)0(l)19.5(s)0(o)-295.7(h)0(a)19.7(d)-312.1(tw)19.8(o)-306.4(s)0(i)20.9(t)0(e)13.8(s)0(:)-295.9(o)0(n)20.8(e)]TJ
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T*
[(us)15.3(ed)-279.8(th)20.7(ei)19.5(r)-289(o)0(w)14.2(n)-289.1(st)20.9(an)19.7(da)19.7(rd)-278.6(ba)19.7(nd)15.1(ag)19.7(in)20.7(g)-289.1(w)0(i)19.8(t)0(h)20.7(i)0(n)-284.5(a)-290.2(DL)18.8(T.)-276.4(Si)15.1(te)19.5(s)-288.9(w)0(e)18.8(r)0(e)]TJ
T*
[(al)13.8(lo)20.7(we)18.8(d)-173.9(t)0(o)-169.4(u)0(s)21(e)-180.8(ei)19.5(th)20.7(er)-164.6(2)-179.6(w)0(e)18.8(e)0(k)19.7(s)-179.5(\(1)20.9(0)-173.9(d)0(a)13.9(y)0(s)-163.3(o)0(f)-169.2(t)0(r)20.7(e)0(a)18.5(t)0(m)19.5(e)0(n)19.7(t)0(\))-169.3(o)0(r)-163.4(4)-179.6(we)18.8(ek)19.7(s)]TJ
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[(\(2)15.1(0)-317.9(d)0(a)19.7(y)0(s)-313(o)0(f)-307.4(t)0(r)20.7(e)0(a)18.5(t)0(m)19.5(e)0(n)13.9(t)0(\))-307.6(a)0(c)18.5(c)0(o)19.7(r)0(d)20.9(i)0(n)15(g)-317.9(to)-307.6(th)15(ei)19.5(r)-317.9(u)0(s)21(u)0(a)19.7(l)-323.8(pr)20.9(ac)18.5(ti)20.6(ce)18.5(.)-320.2(T)0(h)19.6(e)]TJ
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T*
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0 -1.1174 TD
[(tr)15(ea)18.5(tm)19.5(en)19.7(t.)-453.9(To)-458.4(av)19.7(oi)20.7(d)-467.6(c)0(r)19.7(o)0(s)21(s)0(-)15.3(f)0(e)19.7(r)0(t)20.7(i)0(l)20.6(i)0(z)19.6(a)0(t)19.5(i)0(o)14.9(n)-461.9(of)-457.2(pr)20.9(ac)12.8(ti)20.6(ce)18.5(,)-464.2(t)0(h)20.7(e)-468.8(tw)19.8(o)]TJ
0 -1.1116 TD
[(co)13.9(m)15(p)0(r)15.1(e)0(s)19.9(s)0(i)20.9(o)0(n)-295.9(s)0(y)21(s)0(t)15.1(e)0(m)24.2(s)-306.2(we)18.8(re)-297.1(us)15.3(ed)-291.3(in)-296.1(se)19.9(pa)13.9(ra)19.7(te)-297.2(si)20.9(te)19.6(s)-306.2(w)0(i)19.8(t)0(h)20.7(i)0(n)-296.1(e)0(a)18.5(c)0(h)]TJ
T*
[(co)13.9(un)20.8(tr)20.7(y.)-292.5(To)-297.1(av)19.7(oi)20.7(d)-300.6(r)0(e)14(c)0(r)19.7(u)0(i)20.7(t)0(m)19.5(e)0(n)19.7(t)-306.5(an)19.7(d)-300.6(s)0(e)19.9(l)0(e)13.8(c)0(t)19.5(i)0(o)20.7(n)-300.6(bi)15(as)19.9(,)-302.9(a)0(l)19.6(l)-306.5(su)21(it)20.6(ab)19.7(le)]TJ
T*
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8.9663 0 0 8.9663 313.0582 471.0046 Tm
[(Outcomes)-336.6(of)-330.4(treatment)]TJ
/F1 1 Tf
1.1128 -1.6123 TD
[(Limb)-412.1(volume)-416(reduction.)]TJ
/F5 1 Tf
9.843 0 0 9.843 427.6912 456.5479 Tm
[(Lymphedema)-358(volume)-349(was)-356.5(cal-)]TJ
-11.6461 -1.1116 TD
[(culated)-489.5(for)-481.3(each)-485.9(4)-168.1(c)0(m)-488.4(segment)-483.5(of)-486(the)-482.6(limb)-483.9(by)-480.2(using)-489.3(the)]TJ
0 -1.1174 TD
[(truncated)-370.7(cone)-363.8(formula.)]TJ
7.3823 0 0 6.5614 409.4361 439.0298 Tm
(10)Tj
9.843 0 0 9.843 420.3778 434.6078 Tm
[(Absolute)-368(changes)-362.4(were)-364.7(recorded)]TJ
-10.9031 -1.1116 TD
[(on)-290.2(the)-292.6(affected)-295.8(and)-286.7(contralateral)-297.1(limbs)-294.8(at)-285.7(entry)-294.8(to)-290.3(the)-286.8(study,)]TJ
T*
[(on)-324.7(a)-319(biweekly)-323.3(basis)-323.2(during)-323.5(bandaging,)-321.1(and)-321.3(at)-326(the)-321.4(nal)-322.3(visit)]TJ
0 -1.1174 TD
[(\(maintenan)-10.2(ce)-436.5(phase\).)-438.4(For)-435.1(those)-438.6(with)-437.5(bilateral)-440.1(disease,)-440.6(the)]TJ
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[(limb)-564.6(with)-564.2(the)-563.3(largest)-568.8(baseline)-565.3(volume)-562.1(was)-563.8(selected)-566.5(for)]TJ
T*
[(treatment.)-490.7(In)-486(the)-488.4(present)-488(analysis,)-492.5(only)-482.6(the)-488.4(patients)-489.4(with)]TJ
T*
[(swelli)-8.8(ng)-278.7(of)-278.6(the)-281.1(leg)-281.1(were)-284(included.)]TJ
/F1 1 Tf
8.9663 0 0 8.9663 323.0361 344.2393 Tm
[(Euroqol)-387.7(EQ-5D.)]TJ
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9.843 0 0 9.843 397.077 344.2393 Tm
[(The)-322.4(EQ-5D)-331(is)-324.7(a)-330.6(health)-326(index)-329.3(that)-328.4(asks)]TJ
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[(ve)-637.9(questions)-644.5(about)-634.6(the)-638.2(subjects)-639.9(physical)-639(and)-638(mental)]TJ
0 -1.1174 TD
(health.)Tj
7.3823 0 0 6.5614 339.7605 326.6645 Tm
(11)Tj
9.843 0 0 9.843 349.7385 322.2991 Tm
[(When)-272.8(transformed,)-272.4(the)-263.8(results)-267.9(produce)-269.2(a)-267.2(value)-272.9(that)]TJ
-3.7265 -1.1116 TD
[(is)-451.4(on)-451.5(a)-451.5(scale,)-455.9(which)-456.9(includes)-448.9(1.00)-456(\(perfect)-450.1(health\))-453.8(and)-453.7(0)]TJ
T*
[(\(death\).)-192.1(It)-186.6(is)-186.4(possible)-182.6(to)-186.6(achieve)-191(a)-186.6(negative)-191.1(score)-186.1(in)-186.6(conditions)]TJ
0 -1.1174 TD
[(that)-524.2(are)-518.2(considered)-527(worse)-519.9(than)-524.1(death,)-518.2(such)-523.7(as)-521.5(persistent)]TJ
0 -1.1116 TD
[(veget)-8(ative)-658.9(states)-665.4(and/or)-658.7(extreme)-663.4(uncontrolled)-661(pain.)-660(To)]TJ
T*
[(transform)-305.9(the)-298.3(results,)-300.1(weightings)-301.2(were)-301.3(derived)-298.1(from)-299.3(a)-301.8(study)]TJ
0 -1.1174 TD
[(from)-259(multiple)-259.4(countries)-259.9(throughout)-258.9(Europe.)-260(This)-259(assessment)]TJ
0 -1.1116 TD
[(was)-241.3(made)-238.4(at)-233.9(the)-240.7(start)-237.1(of)-238.3(the)-235(study,)-239.3(after)-238.3(10)-232.6(days)-241.5(of)-232.6(treatment,)]TJ
T*
[(and)-286.7(nally)-278.6(after)-284.4(20)-278.7(days)-281.8(of)-278.6(treatment.)]TJ
/F1 1 Tf
8.9663 0 0 8.9663 323.0361 209.9905 Tm
(LYMQOL.)Tj
/F5 1 Tf
9.843 0 0 9.843 372.8692 209.9905 Tm
[(LYMQOL)-473.3(is)-468.7(a)-463(disease-specic)-478(tool)-465.4(that)-466.6(is)]TJ
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[(used)-489.2(to)-486.1(evaluate)-486(the)-482.7(impact)-488.5(of)-486(lymphedema)-489.4(on)-480.3(patients)]TJ
0 -1.1174 TD
(lives.)Tj
7.3823 0 0 6.5614 334.2046 192.4724 Tm
(12)Tj
9.843 0 0 9.843 344.8629 188.0503 Tm
[(It)-324.8(consists)-332.2(of)-330.5(a)-330.6(series)-331.2(of)-330.5(questions)-333.5(that)-328.4(examine)-335.1(the)]TJ
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[(effect)-252.1(that)-247.7(swelling)-247.2(has)-246.2(on)-249.9(the)-246.5(patient.)-244.2(Each)-249.8(question)-251.9(is)-244(rated)]TJ
T*
[(from)-212.9(1)-208.4(\(not)-211.9(at)-210.8(all\))-213.1(to)-209.7(4)-208.4(\()0(a)-210.7(lot\).)-215.4(Similar)-211.9(questions)-212.5(are)-212.9(combined)]TJ
T*
[(to)-284.6(produce)-280.7(a)-278.7(score)-284.1(for)-279.7(the)-286.8(following)-281.9(domains:)]TJ
/F11 1 Tf
7.9702 0 0 7.9702 323.0361 140.0314 Tm
()Tj
/F5 1 Tf
9.843 0 0 9.843 331.9369 138.7842 Tm
(Function)Tj
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7.9702 0 0 7.9702 323.0361 129.0897 Tm
()Tj
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7.9702 0 0 7.9702 323.0361 118.148 Tm
()Tj
/F5 1 Tf
9.843 0 0 9.843 331.9369 116.8441 Tm
(Symptoms)Tj
/F11 1 Tf
7.9702 0 0 7.9702 323.0361 107.2063 Tm
()Tj
/F5 1 Tf
9.843 0 0 9.843 331.9369 105.9023 Tm
(Emotion)Tj
/F11 1 Tf
7.9702 0 0 7.9702 323.0361 96.2078 Tm
()Tj
/F5 1 Tf
9.843 0 0 9.843 331.9369 94.9039 Tm
[(Overall)-339.4(QoL)]TJ
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[(For)-233.5(each)-238.3(domain,)-237.2(a)-238.4(higher)-232.5(score)-238(indicates)-238.2(a)-238.4(greater)-235.9(impact)]TJ
-1.0137 -1.1116 TD
[(on)-388.1(QoL.)-389(The)-391.6(exception)-393.8(to)-382.5(this)-390.4(was)-391(the)-390.5(overall)-390.4(assessment)]TJ
T*
[(where)-285.1(higher)-284.3(scores)-279.2(indicate)-289.2(better)-279.9(QoL.)]TJ
/F3 1 Tf
8.9663 0 0 8.9663 62.022 749.6502 Tm
(2)Tj
46.9476 0 TD
[(FRANKS)-337.3(ET)-338.7(AL.)]TJ
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/F10 1 Tf
8.9663 0 0 8.9663 59.7543 725.7825 Tm
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0 Tc
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[(Cost)-339.1(of)-330.4(care)]TJ
/F5 1 Tf
9.843 0 0 9.843 69.7323 709.3416 Tm
[(Apart)-203.5(from)-195.6(the)-200.4(treatment)-199.3(group)-201.3(allocation,)-202.8(there)-198(is)-198(much)-196.9(to)]TJ
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[(in)-221.2(terms)-220.9(of)-215.3(not)-216.5(only)-223.4(both)-217.6(treatments)-223.2(given)-214.1(but)-222.3(also)-218.6(the)-217.7(cost)-218.6(of)]TJ
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[(care)-284.3(delivery.)-285.5(This)-282(study)-281.9(included)-282.1(the)-281.1(following:)]TJ
/F11 1 Tf
7.9702 0 0 7.9702 69.7323 661.3226 Tm
()Tj
/F5 1 Tf
9.843 0 0 9.843 78.633 660.0187 Tm
[(Disposable)-336.6(product)-337.3(usage)]TJ
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7.9702 0 0 7.9702 69.7323 650.3809 Tm
()Tj
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[(Type)-640.3(of)-641.5(care)-641.4(delivery;)-640.4(multilayer)-642.9(bandaging)-640.2(used,)]TJ
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[(massage,)-338(physiotherapy,)-336.9(and)-332.8(exercise)-341.7(management.)]TJ
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[(Th)19.6(e)-422.7(c)0(o)13.9(s)0(t)20.9(i)0(n)20.7(g)0(s)-416.7(f)0(o)20.9(r)-421.5(th)20.7(is)-416.8(an)19.7(al)19.5(ys)21(is)-416.8(we)18.8(re)-412.3(un)15.1(de)19.7(rt)20.7(ak)19.7(en)-412.3(fr)15.2(om)-412.4(th)20.7(e)]TJ
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[(vi)14.9(de)19.7(s)-237(g)0(o)20.8(o)0(d)-226.8(e)0(v)19.7(i)0(d)20.7(e)0(n)13.9(c)0(e)-229.1(o)0(n)-226.8(t)0(h)20.7(e)-238.4(un)20.8(it)-232.8(co)19.7(st)20.9(s)-237(o)0(f)-226.8(d)0(i)15(s)0(p)21(o)0(s)21(a)0(b)19.7(l)0(e)19.6(s)-237.1(us)15.3(in)20.7(g)-237.2(t)0(h)20.7(e)]TJ
T*
[(Br)14.1(it)20.6(is)20.9(h)-289.1(N)0(a)18.8(t)0(i)20.6(o)0(n)20.8(a)0(l)-280(F)0(o)21(r)0(m)19.7(u)0(l)20.7(a)0(r)14(y)]TJ
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(13)Tj
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[(an)19.7(d)-289.1(D)0(r)20(u)0(g)-278.7(T)0(a)18.5(r)0(i)20.7(f)0(f)15.1(.)]TJ
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(14)Tj
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[(Th)19.6(e)-290.2(p)0(r)20.9(i)0(c)19.6(e)-290.2(of)]TJ
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[(pr)15.1(od)20.8(uc)19.7(ts)-382.3(wa)18.8(s)-386.8(u)0(p)15.1(r)0(a)19.7(t)0(e)19.6(d)-392.8(fr)20.9(om)-377.8(th)20.7(e)-393.9(i)0(n)20.7(i)0(t)20.6(i)0(a)19.6(l)-392.9(co)19.7(st)15.1(in)20.7(g)-387(f)0(r)15.1(o)0(m)-377.8(2)0(0)20.8(1)0(4)-382.3(t)0(o)]TJ
0 -1.1116 TD
[(20)15.1(21)-226.8(to)-227(re)19.7(e)19.8(ct)-228.1(in)20.7(a)19.8(ti)14.8(on)-226.8(ww)19.1(w)21.1(.)0(b)18.5(a)0(n)19.7(k)0(o)20.8(f)0(e)19.7(n)0(g)20.8(l)0(a)19.6(n)0(d)26.6(.)13.9(co)25.4(.)13.9(u)0(k)15.1(/)0(m)19.5(o)0(n)20.8(e)0(t)19.5(a)0(r)19.7(y)0(-)]TJ
T*
[(po)15.1(li)20.6(cy)19.7(/i)20.6(n)21(at)19.5(io)20.7(n/)14.9(in)20.7(a)19.8(ti)20.6(on)20.8(-c)19.7(al)19.6(cu)13.9(la)19.6(to)20.7(r.)-586.2(Th)19.6(e)-601.3(c)0(o)19.7(s)0(t)-589.6(e)0(s)14.1(t)0(i)20.6(m)0(a)18.4(t)0(e)19.6(s)-599.9(fo)20.9(r)]TJ
0 -1.1174 TD
[(he)19.7(al)13.8(th)-313.4(pr)20.9(of)20.9(es)19.9(si)15.1(on)20.8(al)19.5(s)-323.4(w)0(e)18.8(r)0(e)-320.1(d)0(e)19.7(r)0(i)20.7(v)0(e)19.7(d)-323.6(fr)20.9(om)-320.2(da)19.7(ta)-314.5(pr)20.9(ov)20.8(id)20.7(ed)-320.1(by)-313.2(th)20.7(e)]TJ
0 -1.1116 TD
[(Pe)14.1(rs)21.1(on)20.8(al)-170.5(So)15.2(ci)19.5(al)-170.5(Se)19.8(rv)20.9(ic)13.8(es)-170.2(Re)18.6(se)19.9(ar)19.7(ch)-176.1(Un)20(it)-175.2(\(P)21(SS)21.2(RU)18.9(\))-185.4(U)0(.)23.4(K)0(.)-172.4(2)0(0)20.8(2)0(1)15.1(.)]TJ
7.3823 0 0 6.5614 291.5716 538.3558 Tm
(15)Tj
/F10 1 Tf
8.9663 0 0 8.9663 59.7543 509.2723 Tm
[(Statistical)-336.1(methods)]TJ
/F5 1 Tf
9.843 0 0 9.843 69.7323 492.8314 Tm
[(In)20.9(it)14.8(ia)19.5(l)-387.1(u)0(n)15.1(i)0(v)20.7(a)0(r)19.7(i)0(a)19.5(t)0(e)-383.6(a)0(n)19.7(a)0(l)19.5(y)0(s)15.3(i)0(s)-376.5(c)0(o)13.9(m)0(p)19.6(a)0(r)19.7(i)0(n)20.7(g)-392.8(th)20.7(e)-393.9(t)0(w)19.8(o)-392.8(gr)20.9(ou)20.8(ps)-382.1(wa)18.8(s)]TJ
-1.0137 -1.1116 TD
[(pe)13.9(rf)20.9(or)20.9(me)18.4(d)-237.2(b)0(y)-226.8(u)0(s)15.3(i)0(n)20.7(g)-237.2(th)20.7(e)-238.4(C)0(h)14(i)0(-)20.7(s)0(q)21(u)0(a)19.7(r)0(e)19.7(d)-243(te)19.6(st)20.9(.)-239.6(F)0(o)21(r)-237.2(co)19.7(nt)20.7(in)15(uo)20.8(us)-226.6(da)19.7(ta)13.8(,)]TJ
T*
[(St)15.1(ud)20.8(en)19.7(t)20.7(s)]TJ
/F7 1 Tf
4.1815 0 TD
(t)Tj
/F5 1 Tf
.2707 0 TD
[(-t)20.7(es)19.9(t)-479.3(o)0(r)-462.9(a)0(n)19.7(a)0(l)19.5(y)0(s)15.3(i)0(s)-462.9(o)0(f)-468.7(v)0(a)19.7(r)0(i)20.7(a)0(n)19.7(c)0(e)-471.1(w)0(a)18.8(s)-473.2(em)18.5(pl)20.7(oy)20.8(ed)-469.9(de)19.7(-)]TJ
-4.4523 -1.1174 TD
[(pe)13.9(nd)20.8(in)20.7(g)-208.4(o)0(n)-203.8(t)0(h)20.7(e)-209.6(nu)20.8(mb)19.6(er)-204.9(of)-198(ou)15.1(tc)19.6(om)19.6(es)-199(wi)19.8(th)15(in)-198.2(th)20.7(e)-215.4(g)0(r)20.9(o)0(u)20.8(p)0(s)21(.)-210.8(Fo)15.2(r)-208.4(t)0(h)20.7(e)]TJ
0 -1.1116 TD
[(co)13.9(m)15(p)0(a)13.9(r)0(i)20.7(s)0(o)21(n)-271.8(of)-261.4(ma)18.4(tc)19.6(he)19.7(d)-271.8(d)0(a)19.7(t)0(a)19.6(,)-268.4(th)20.7(e)-273(p)0(a)19.7(i)0(r)20.7(e)0(d)]TJ
/F7 1 Tf
15.9371 0 TD
(t)Tj
/F5 1 Tf
.2707 0 TD
[(-t)15(es)19.9(t)-266.2(w)0(a)13(s)-265.8(us)15.3(ed)19.7(.)]TJ
-15.1941 -1.1116 TD
[(Th)19.6(e)-267.2(f)0(r)20.9(e)0(q)19.7(u)0(e)19.7(n)0(c)13.9(y)-260.3(of)-255.6(vi)20.7(si)15.1(ts)-249.8(fo)15.1(r)-260.2(b)0(a)13.9(n)0(d)20.8(a)0(g)19.7(e)-267.2(ch)19.7(an)19.7(ge)-256.8(wa)18.8(s)-260.1(m)0(u)19.6(l)0(t)14.8(i)0(p)20.7(l)0(i)20.6(e)0(d)]TJ
-1.0137 -1.1174 TD
[(by)-278.7(th)20.7(e)-290.2(a)0(v)19.7(e)0(r)19.7(a)0(g)19.7(e)-290.2(co)19.7(st)-272.8(of)-278.6(ba)19.7(nd)20.8(ag)19.7(es)-279.6(fo)20.9(r)-289(e)0(a)18.5(c)0(h)-279.8(p)0(a)19.7(t)0(i)20.6(e)0(n)19.7(t)-283.5(to)-278.8(de)19.7(ri)20.7(ve)-279.8(an)]TJ
0 -1.1116 TD
[(ov)15.1(er)19.7(al)19.5(l)-179.8(c)0(o)19.7(s)0(t)-169.2(o)0(f)-169.2(b)0(a)19.7(n)0(d)20.8(a)0(g)19.7(e)0(s)-170.2(u)0(s)21(e)0(d)19.7(.)-182(Th)19.6(e)-175(c)0(o)13.9(s)0(t)-169.2(o)0(f)-163.4(h)0(e)13.9(a)0(l)19.5(t)0(h)-169.4(p)0(r)20.9(o)0(f)20.9(e)0(s)19.9(s)0(i)15.1(o)0(n)20.8(a)0(l)19.6(s)0()]TJ
T*
[(ti)14.8(me)-286.8(wa)18.8(s)-300.4(d)0(e)19.7(t)0(e)19.5(r)0(m)19.7(i)0(n)20.7(e)0(d)-291.3(a)0(s)-285.4(t)0(h)20.7(e)-301.8(fr)20.9(eq)19.7(ue)19.7(nc)13.9(y)-294.8(o)0(f)-290.1(v)0(i)20.7(s)0(i)20.9(t)0(s)-290.1(m)0(u)19.6(l)0(t)20.6(i)0(p)20.7(l)0(i)20.6(e)0(d)-291.3(b)0(y)]TJ
0 -1.1174 TD
[(th)15(e)-296(a)0(v)19.7(e)0(r)14(a)0(g)19.7(e)-296(ti)20.6(me)-292.6(fo)20.9(r)-300.6(e)0(a)18.5(c)0(h)-291.3(p)0(a)19.7(t)0(i)20.6(e)0(n)19.7(t)0(,)-292.6(w)0(h)20(i)0(c)19.6(h)-300.6(wa)18.8(s)-294.6(t)0(h)15(e)0(n)-285.6(m)0(u)19.6(l)0(t)14.8(i)0(p)20.7(l)0(i)20.6(e)0(d)]TJ
0 -1.1116 TD
[(by)-307.5(th)20.7(e)-319(c)0(o)19.7(s)0(t)-307.4(p)0(e)19.7(r)-317.8(ho)20.8(ur)-307.4(of)-301.7(ea)18.5(ch)-308.6(he)19.7(al)19.5(th)-307.6(pr)20.9(of)15.1(es)19.9(si)20.9(on)20.8(al)13.8(s)-301.5(ti)14.8(me)18.4(.)-314.5(T)0(h)19.6(i)0(s)]TJ
T*
[(wa)18.8(s)-225.5(d)0(e)19.7(r)0(i)15(v)0(e)19.7(d)-225.7(fr)20.9(om)-210.8(es)14.1(ti)20.6(ma)18.4(te)19.6(s)-225.5(p)0(u)20.8(b)0(l)20.7(i)0(s)20.9(h)0(e)13.9(d)-220(in)-215.4(th)20.7(e)-226.9(U)0(n)20(i)0(t)20.6(e)0(d)-216.5(K)0(i)19.8(n)0(g)20.8(d)0(o)15.1(m)15(.)]TJ
T*
[(Th)19.6(us)15.3(,)-210.8(a)0(l)19.5(l)-214.3(co)19.7(st)20.9(in)15(gs)-197.8(re)14(la)19.6(te)19.6(d)-214.2(t)0(o)-203.9(t)0(h)20.7(e)-209.6(U.)17.6(K.)-207(NH)19.1(S)-208.3(a)0(n)13.9(d)-208.4(we)18.8(re)-204.9(ex)19.7(pr)15.1(es)19.9(se)19.9(d)]TJ
0 -1.1174 TD
[(as)-262.4(GB)-263.3(po)20.8(un)20.8(ds)15.3(.)-268.4(T)0(h)19.6(e)-273(pr)20.9(ot)20.7(oc)19.7(ol)-261.5(wa)18.8(s)-271.6(a)0(p)19.7(p)0(r)20.9(o)0(v)20.8(e)0(d)-262.5(b)0(y)-261.4(t)0(h)20.7(e)-273(Ca)18.6(mb)19.6(ri)20.7(dg)20.8(e)]TJ
0 -1.1116 TD
[(Ce)18.6(nt)14.9(ra)19.7(l)-271.9(R)0(E)18.6(C)-267.1(\(1)20.9(3/)15(EE)18.5(/0)20.7(15)20.8(4\))-261.4(on)-261.4(8)-266(J)0(u)15.3(l)0(y)-255.8(2)0(0)15.1(1)0(3)20.8(.)]TJ
/F3 1 Tf
8.9663 0 0 8.9663 59.7543 314.7023 Tm
(Results)Tj
/F10 1 Tf
0 -1.8336 TD
[(Patient)-337.7(characteristics)-336.6(and)-329.4(treatment)-335.5(groups)]TJ
/F5 1 Tf
9.843 0 0 9.843 69.7323 281.8204 Tm
[(In)-284.4(total,)-281.2(264)-285.5(patients)-282(were)-284(entered)-287.8(into)-281.1(the)-286.8(main)-283.4(study,)-279.6(of)]TJ
-1.0137 -1.1116 TD
[(whom)-236.9(176)-233.7(had)-240.6(chronic)-234.8(swelling)-235.7(of)-238.3(the)-235(leg.)-238.4(Of)-233.4(these,)-235.8(165)-233.7(had)]TJ
0 -1.1174 TD
[(information)-251(on)-249.9(bandage)-247.4(type)-247.6(and)-246.4(frequency)-249.5(with)-247.4(at)-251.2(least)-249.8(one)]TJ
0 -1.1116 TD
[(follow-up)-247.1(assessment.)-248.9(Table)-245.3(1)-237.2(compares)-249.5(the)-240.7(90)-244.1(patients)-241.7(who)]TJ
T*
[(were)-226.4(treated)-218.8(with)-218.6(Coban)-220.8(2)-220(with)-218.6(the)-223.5(75)-215.3(who)-223(were)-220.7(managed)-219.8(by)]TJ
T*
[(using)-224.3(the)-223.5(local)-227(standard)-224.2(care)-221(who)-223(had)-223.3(costs)-225.3(attributed)-226.9(to)-221.2(their)]TJ
0 -1.1174 TD
[(treatment.)-208.5(Although)-205.8(most)-201.4(of)-203.8(the)-206.2(baseline)-208.2(clinical)-202.9(results)-210.3(were)]TJ
0 -1.1116 TD
[(similar,)-295.9(other)-294.8(factors)-297.9(were)-295.6(substantially)-299.1(different.)-298.1(The)-293.6(prev-)]TJ
T*
[(alence)-270.6(of)-261.4(current)-263.5(cellulitis)-261.6(was)-264.3(greater)-264.7(in)-261.5(the)-263.8(patients)-264.8(treated)]TJ
0 -1.1174 TD
[(with)-316.6(Coban)-313(2)-312.1(\(10.23%)-316.3(vs.)-310.7(0%\))-315.4(compared)-313(with)-316.6(the)-309.9(standard)]TJ
0 -1.1116 TD
[(care.)-253.2(However,)-245.6(most)-247.5(centers)-247.2(would)-248.4(not)-245.3(commence)-252.1(treatment)]TJ
T*
[(if)-359.4(an)-354.7(acute)-354.7(cellulitis)-359.5(was)-356.5(suspected.)-356.4(Moreover,)-355.2(the)-355.9(Interna-)]TJ
0 -1.1174 TD
[(tional)-434.4(Society)-436.4(of)-428.4(Lymphology)-434(severity)-437.4(scale)-435.1(showed)-428.9(sub-)]TJ
0 -1.1116 TD
[(stantially)-417(more)-415.7(patients)-414.5(in)-411.3(stage)-410.9(III)-412.1(in)-411.3(the)-413.5(Coban)-410.9(2)-415.8(group)]TJ
T*
[(\(24.44%)-253(vs.)-247.3(9.33%\),)-249.6(with)-247.4(this)-252.1(being)-248.7(largely)-252.2(counterbalanced)]TJ
T*
[(by)-284.4(patients)-282(in)-278.8(late)-283.5(stage)-284.2(II)-278.6(\(31.11%)-281.8(vs.)-281.9(56.00%\).)]TJ
1.0137 -1.1174 TD
[(As)-296.6(part)-299.4(of)-301.7(the)-298.3(outcomes)-300.3(in)-296.1(this)-298.2(study,)-302.6(patients)-299.3(were)-301.3(eval-)]TJ
-1.0137 -1.1116 TD
[(uated)-284.4(in)-284.6(respect)-281.8(of)-284.4(the)-281.1(duration)-280.9(of)-284.4(treatment)-285.7(in)-278.8(the)-281.1(intensive)]TJ
T*
[(phase.)-247.2(Of)-244.9(the)-246.5(90)-244.1(patients)-247.5(treated)-247.6(with)-241.7(Coban)-243.9(2,)-246.4(73.33%)-246.2(were)]TJ
0 -1.1174 TD
[(managed)-450.2(over)-443.3(4)-444.6(weeks)-452(compared)-445.5(with)-443.3(40.00%)-447.7(of)-445.7(the)-442.3(75)]TJ
0 -1.1116 TD
[(patients)-287.8(in)-278.8(the)-281.1(standard)-281.7(care)-284.3(group.)]TJ
/F10 1 Tf
8.9663 0 0 8.9663 310.8472 725.7825 Tm
[(Health-related)-336.2(quality)-332.7(of)-336.7(life)]TJ
/F5 1 Tf
9.843 0 0 9.843 320.8251 709.3416 Tm
[(The)-380(effect)-378.8(of)-382.3(treatment)-383.6(on)-376.6(the)-384.7(patient)-379.1(was)-385.3(evaluated)-383.4(by)]TJ
-1.0137 -1.1116 TD
[(comparing)-307.3(HRQoL)-303.2(at)-308.8(entry)-306.3(into)-304.2(the)-304.1(study)-304.9(and)-304(at)-303(the)-304.1(end)-309.7(of)]TJ
0 -1.1174 TD
[(the)-229.2(intensive)-237.1(phase)-232.3(\(Table)-234.9(2\).)-230.2(The)-236.1(paired)-233.7(differences)-235.5(for)-233.6(EQ-)]TJ
0 -1.1116 TD
[(5D)-279.5(indicate)-283.4(a)-278.7(substantial)-285.3(improvement)-282.1(in)-278.8(health)-285.7(status,)-281.8(with)]TJ
T*
[(an)-308.6(overall)-309.8(health)-314.5(gain)-311(of)-307.4(7.7%.)-310.7(A)-307.2(similar)-309.8(improveme)-9(nt)-307.6(was)]TJ
0 -1.1174 TD
[(noted)-277.5(in)-284.5(the)-281.1(personal)-281.7(health)-285.7(score)-278.3(of)-284.4(8.29%.)]TJ
1.0137 -1.1116 TD
[(There)-325.8(were)-330.1(similar)-327(improvements)-329.1(in)-324.9(HRQoL)-326.3(when)-329(eval-)]TJ
-1.0137 -1.1116 TD
[(uated)-537.8(by)-537.8(the)-540.2(LYMQOL)-542.4(questionnaire,)-545.5(with)-541.2(all)-540.4(domains)]TJ
T*
[(demonstrating)-691.9(improvements)-691.9(over)-685.2(the)-690(treatment)-688.9(period)]TJ
0 -1.1174 TD
[(\(as)-286.5(indicated)-290.3(by)-284.4(a)-290.2(reduction)-288.9(in)-284.5(domain)-285.6(scores\).)-289.5(The)-287.9(use)-286.5(of)-284.4(a)]TJ
0 -1.1116 TD
[(scale)-325.7(to)-324.9(determine)-331.6(overall)-327.1(QoL)-327.9(closely)-326.9(mirrored)-328(that)-328.4(of)-324.7(the)]TJ
T*
[(Visual)-279.4(Analogue)-288.6(Scale)-279.7(\(VAS\))-283.5(self-assessment)-286.6(in)-284.6(EQ-5D.)]TJ
1.0137 -1.1174 TD
[(The)-420.4(results)-429.2(showed)-423.2(a)-422.7(slightly)-423.8(greater)-426(reduction)-427.2(in)-422.8(limb)]TJ
-1.0137 -1.1116 TD
[(volume)-228(with)-230.2(Coban)-232.3(2)-231.5(compared)-232.4(with)-230.2(the)-229.2(standard)-229.9(treatments)]TJ
T*
[(\(1.204)-164.4(L)-238.4(vs.)-241.6(1.077)-163.3(L\),)-242.9(though)-237.1(this)-240.6(did)-233.8(not)-239.6(approach)-242.7(statistical)]TJ
0 -1.1174 TD
[(signicance)-316.2(\(Table)-315.5(3\).)-316.6(This)-316.6(result)-313.1(was)-316.2(mirrored)-316.5(by)-313.2(the)-315.6(EQ-)]TJ
0 -1.1116 TD
[(5D,)-306(though)-306.2(the)-304.1(self-assessed)-311.8(VAS)-304.4(showed)-308(greater)-310.8(improve-)]TJ
T*
[(ments)-278.5(in)-284.5(the)-281.1(standard)-281.7(care)-284.3(group)-281.9(\(Table)-280.9(3\).)]TJ
1.0137 -1.1174 TD
[(In)-422.6(LYMQOL,)-430.7(a)-422.7(low)-424.8(score)-428.1(indicates)-428.3(less)-425.8(impact)-430.9(on)-422.7(the)]TJ
-1.0137 -1.1116 TD
[(patient)-425.1(for)-423.7(the)-425(given)-427.3(domains.)-428.2(From)-425.9(these)-422.5(analyses,)-430.2(there)]TJ
T*
[(were)-393.5(similar)-401.9(reductions)-393.5(in)-399.7(scores)-394.4(\(better)-396.1(health\))-401.9(in)-394(all)-396.4(do-)]TJ
T*
[(mains)-330.4(of)-324.7(the)-332.9(prole)-330.3(between)-329(the)-332.9(two)-326.8(groups.)-326.6(There)-331.5(was)-333.4(no)]TJ
0 -1.1174 TD
[(statistical)-286.7(difference)-280.6(betwe)-8.8(en)-279.8(the)-281.1(two)-280.8(groups.)]TJ
1.0137 -1.1116 TD
[(Table)-262.6(4)-266(gives)-271.6(the)-263.8(number)-268.2(of)-267.1(treatment)-268.4(visits)-265.8(and)-269.4(the)-263.8(costs)]TJ
-1.0137 -1.1116 TD
[(of)-284.4(bandages)-294.3(used)-287.6(in)-284.5(the)-286.8(intensive)-294.7(phase)-284.1(by)-290.2(treatment.)-289.1(There)]TJ
0 -1.1174 TD
[(was)-270.1(clear)-268.3(difference)-274.9(in)-267.3(the)-269.5(mean)-272.9(number)-268.2(of)-267.1(visits)-271.6(in)-267.3(the)-269.5(rst)]TJ
0 -1.1116 TD
[(10)-457.2(days)-454.6(with)-460.6(substantially)-460.4(lower)-462.7(Coban)-457(2)-456.1(visits,)-459.3(with)-460.5(an)]TJ
T*
[(overall)-281(difference)-280.6(of)-278.6(2.75)-277.4(visits)-277.3(per)-280.9(patient.)-278.8(Between)-283.9(11)-278.7(and)]TJ
0 -1.1174 TD
[(20)-295.9(days,)-296.8(there)-301.7(was)-298.9(greater)-299.2(activity)-299.6(using)-299.2(Coban)-295.7(2.)-298.3(This)-299.3(was)]TJ
0 -1.1116 TD
[(due)-465.2(to)-468.9(the)-471.1(larger)-469.8(proportion)-466.2(of)-468.7(patients)-472.1(on)-468.7(Coban)-468.5(2)-467.6(that)]TJ
T*
[(continued)-450.2(the)-448.1(intensive)-450.2(phase)-451.1(beyond)-451.3(the)-448.1(initial)-447.3(10)-451.4(days.)]TJ
T*
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[(i)16.1(n)-375.5(W)13.9(a)15(le)25.3(s)-375.3(b)16.2(y)-369.7(H)0(u)25.7(m)15(ph)26.6(r)16.2(e)0(y)25.4(s)-375.3(e)15(t)-369.8(al)25.3(.)]TJ
7.3823 0 0 6.5614 182.8346 378.4251 Tm
-.0162 Tc
(22)Tj
9.843 0 0 9.843 193.7763 374.0597 Tm
-.0156 Tc
[(The)-15.6(y)-376.1(ex)-15.6(a)9.8(m)-.6(i)-15.6(n)10.9(ed)-391.1(the)-392.2(c)-.6(os)-15.6(t)-374.8(o)-15.6(f)]TJ
-13.3856 -1.1174 TD
0 Tc
[(t)16.1(r)0(e)25.5(a)0(t)25.3(m)15(e)15(n)0(t)-192.4(r)16.2(et)25.3(r)16.2(o)0(s)26.8(p)0(e)25.4(c)15(ti)26.3(v)16.2(e)0(l)25.3(y)-202.7(o)16.2(v)0(e)25.4(r)-202.7(3)-202.7(m)15(on)26.6(th)26.5(s)-202.5(a)15(nd)-192.3(a)-203.8(f)16.2(u)16.2(r)0(t)26.5(h)0(e)25.4(r)-202.7(3)-202.7(m)15(on)26.6(t)16.1(h)0(s)]TJ
0 -1.1116 TD
[(p)16.2(r)0(o)26.6(s)0(p)26.8(e)15(ct)25.3(i)16.1(v)0(e)-256.8(s)0(t)26.7(u)16.2(dy)26.6(.)-268.4(D)15.3(ur)26.6(i)16.1(n)0(g)-255.6(t)16.1(he)-256.8(p)16.2(r)0(o)26.6(s)0(p)26.8(e)15(ct)25.3(i)16.1(v)0(e)-256.8(p)16.2(ha)25.4(se)25.6(,)-268.4(t)16.1(h)16.2(e)0(y)-256.8(d)16.2(em)24.2(o)16.2(n)0(-)]TJ
T*
[(st)26.7(r)16.2(a)0(t)25.3(e)15(d)-358.2(a)15(n)-352.4(i)16.1(nc)25.4(r)16.2(e)0(a)24.3(s)0(e)-343(i)16.1(n)-352.4(E)15(Q-)25.8(5D)-342.9(o)16.2(f)-352.4(0.)24.3(1)16.2(3)16.2(6)-352.4(an)25.4(d)-352.4(a)-353.6(VA)24.9(S)-352.3(o)0(f)-342(1)16.2(4.)30(69)26.6(.)]TJ
T*
[(C)15.2(l)0(e)25.3(a)15(rl)26.5(y,)-223.4(t)16.1(h)0(e)25.4(y)-237.2(a)15(c)15(h)0(i)26.5(e)15(ve)25.4(d)-237.2(m)15(uc)25.4(h)-237.2(g)16.2(r)16.2(e)0(a)24.3(t)16.1(er)-228(i)16.1(m)15(pr)26.6(o)16.2(v)0(e)25.4(m)15(e)15(n)0(t)26.5(s)-237(t)16.1(h)0(a)25.4(n)-237.2(i)16.1(n)-237.2(t)16.1(h)0(e)]TJ
25.504 5.5639 TD
[(pr)26.6(es)25.6(e)15(n)0(t)-163.6(s)16.4(tu)26.5(d)16.2(y)0(.)-165.8(I)16.2(t)-174(i)0(s)-163.4(p)16.2(os)26.8(s)16.4(i)0(b)26.5(l)0(e)-164.8(t)16.1(h)16.2(a)0(t)-164.8(t)16(he)-164.6(d)16.2(u)0(r)26.6(a)15(ti)26.3(o)16.2(n)-179.6(o)16.2(f)-173.9(tr)26.5(e)15(a)0(t)25.3(m)14.9(en)25.4(t)-174(h)16.2(ad)-164.6(a)15(n)]TJ
0 -1.1116 TD
[(in)26.5(u)26.8(e)15(n)0(c)25.4(e)-509.1(on)-497.5(th)26.5(e)-509.1(m)0(a)24.2(g)16.2(ni)26.5(t)16.1(u)0(d)26.6(e)-509.1(of)-497.5(th)26.5(e)-509.1(c)0(h)25.4(a)15(ng)26.6(e.)-501(M)15.3(o)16.2(re)25.5(o)16.2(v)0(e)25.4(r)16.2(,)-510.3(t)0(h)26.5(e)]TJ
0 -1.1174 TD
[(ba)25.4(se)25.6(l)16.1(i)0(n)26.5(e)-192.3(EQ)24.5(-)16.2(5)0(D)-181.6(v)16.2(al)25.3(u)16.2(e)0(s)-181.7(i)16.1(n)-196.9(t)16.1(h)16.2(e)-198.1(p)16.2(r)16.2(e)0(v)25.4(i)16.1(ou)26.6(s)-196.7(s)16.4(t)16(u)0(d)26.6(y)-191.2(we)24.6(r)16.2(e)-198.1(s)16.4(u)16.2(bs)26.8(ta)25.3(n)16.2(t)0(i)26.3(a)15(ll)26.3(y)]TJ
0 -1.1116 TD
[(lo)26.5(we)24.6(r)-473.4(a)15(t)-473.5(0)16.2(.)13.9(4)16.2(01)-457.2(c)15(o)0(m)25.4(p)16.2(ar)25.5(e)15(d)-473.4(w)15.3(i)0(t)26.3(h)-473.4(0)16.2(.)13.9(5)16.2(8)0(7)-457.2(i)0(n)-457.3(t)0(h)26.5(e)-474.6(p)16.2(r)0(e)25.5(s)16.4(en)25.4(t)-473.5(s)16.4(t)16(u)0(d)26.6(y)0(.)]TJ
T*
[(A)-226.6(s)0(i)26.7(m)0(i)25.2(l)16.1(ar)-216.4(p)16.2(a)15(tt)26.3(e)15(r)0(n)-215.3(w)15.3(as)-216.3(s)16.4(e)15(en)-216.5(i)16.1(n)-225.7(th)26.5(e)-226.9(V)15.3(AS)-216(w)15.3(i)16(th)-215.4(a)-226.9(b)16.2(a)15(s)0(e)25.6(l)0(i)26.3(n)16.2(e)-226.9(s)0(c)25.6(o)16.2(re)-216.4(o)16.2(f)]TJ
T*
[(47)26.6(.)13.9(0)0(7)26.6(,)-262.6(co)25.4(m)15(p)0(a)25.4(r)16.2(ed)-256.8(w)15.3(i)16.1(th)-255.8(6)16.2(0)0(.)30(7)0(6)-255.6(i)16.1(n)-266(t)0(h)26.5(e)-267.2(p)16.2(r)0(e)25.5(s)16.4(en)25.4(t)-266.2(s)0(t)26.7(u)16.2(dy)26.6(.)]TJ
ET
62.022 709.512 490.167 .22681 re
f
62.022 412.044 490.167 .22678 re
f
62.022 690.803 490.167 .28345 re
f
BT
/F9 1 Tf
9.845 0 0 9.845 89.0078 725.1588 Tm
(Table)Tj
/F5 1 Tf
3.0002 0 TD
(3.)Tj
/F9 1 Tf
1.2496 0 TD
[(Limb)-334.5(Volume)-331.2(Reduction,)-337.9(EQ-)]TJ
/F5 1 Tf
13.308 0 TD
(5)Tj
/F9 1 Tf
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[(D)-335.8(and)-332(LYMQOL)-339.8(Scores:)-334.8(Comparison)-336.2(of)-331.2(Change)-337.2(in)-331.6(Scores)]TJ
-10.3308 -1.0135 TD
[(Between)-332.7(Treatment)-334.5(Groups)-337(in)-331.6(Patients)-337(with)-334.7(Leg)-332.2(Lymphedema)]TJ
/F5 1 Tf
-3.1326 -1.8427 TD
(N)Tj
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3.7488 0 TD
[(Mean)-3657(SD)-3394.6(Mean)-334.4(diff)-2636.1(95%)-332.2(condence)-336.1(intervals)]TJ
/F5 1 Tf
31.1249 0 TD
(t)Tj
/F7 1 Tf
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[(\(df)-83.8(\))]TJ
/F5 1 Tf
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(p)Tj
-48.6655 -1.8946 TD
[(Limb)-334.7(volume)-336.7(reduction)-334.1(\(L\))]TJ
1.002 -1.0135 TD
[(Coban)-335.3(2)-2742.1(9)0(0)-3186.5(1.204)-3128.5(2.201)-3761.9(0.127)]TJ
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[(0.457)-335.6(to)-336.2(0.713)-6428.1(0.43)-334.6(\(163\))-2630.9(0.67)]TJ
-27.7735 -1.0135 TD
[(Standard)-2630.4(75)-3186.5(1.077)-3128.5(1.453)]TJ
-1.002 -1.313 TD
(EQ-5D)Tj
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[(Coban)-335.3(2)-2742.1(7)0(2)-3186.5(0.084)-3128.5(0.196)-3761.9(0.014)]TJ
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[(0.046)-335.6(to)-336.2(0.077)-6428.1(0.43)-334.6(\(133\))-2630.9(0.67)]TJ
-27.7735 -1.0135 TD
[(Standard)-2630.4(63)-3186.5(0.070)-3128.5(0.175)]TJ
-1.002 -1.3129 TD
[(Health)-337.7(today)-334.5(\(VAS\))]TJ
1.002 -1.0135 TD
[(Coban)-335.3(2)-2742.1(7)0(1)-3186.5(7.12)-3127.5(14.13)]TJ
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[(7.54)-334.6(to)-336.1(2.63)-7429.1(0.95)-334.6(\(134\))-2630.9(0.34)]TJ
-27.7735 -1.0135 TD
[(Standard)-2630.4(65)-3186.5(9.57)-3127.5(15.86)]TJ
-1.002 -1.3129 TD
(LYMQOL)Tj
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1.002 -1.0077 TD
[(Coban)-335.3(2)-2742.1(7)0(2)]TJ
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9.8241 0 TD
(-)Tj
/F5 1 Tf
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[(1.54)-3628.5(3.61)]TJ
-10.3769 -1.0135 TD
[(Standard)-2630.4(61)]TJ
/F6 1 Tf
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(-)Tj
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[(2.08)-3628.5(4.51)]TJ
/F6 1 Tf
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/F5 1 Tf
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(0.54)Tj
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/F5 1 Tf
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[(1.96)-334.6(to)-336.1(2.48)-7429.1(0.77)-334.6(\(131\))-2630.9(0.44)]TJ
-28.7754 -1.3187 TD
(Appearance)Tj
1.002 -1.0077 TD
[(Coban)-335.3(2)-2742.1(7)0(1)]TJ
/F6 1 Tf
9.8241 0 TD
(-)Tj
/F5 1 Tf
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[(1.60)-3628.5(4.16)]TJ
-10.3769 -1.0135 TD
[(Standard)-2630.4(61)]TJ
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[(1.64)-3628.5(4.08)]TJ
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[(1.46)-334.6(to)-336.1(1.39)-7429.1(0.05)-334.6(\(130\))-2630.9(0.96)]TJ
-28.7754 -1.3187 TD
(Symptoms)Tj
1.002 -1.0077 TD
[(Coban)-335.3(2)-2742.1(6)0(1)]TJ
/F6 1 Tf
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/F5 1 Tf
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[(1.18)-3628.5(3.26)]TJ
-10.3769 -1.0135 TD
[(Standard)-2630.4(51)]TJ
/F6 1 Tf
9.8241 0 TD
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[(1.47)-3628.5(2.60)]TJ
/F6 1 Tf
10.8376 0 TD
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[(1.41)-334.6(to)-336.1(0.83)-7429.1(0.51)-334.6(\(110\))-2630.9(0.61)]TJ
-28.7754 -1.313 TD
(Emotion)Tj
1.002 -1.0135 TD
[(Coban)-335.3(2)-2742.1(7)0(2)]TJ
/F6 1 Tf
9.8241 0 TD
(-)Tj
/F5 1 Tf
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[(1.19)-3628.5(3.47)]TJ
-10.3769 -1.0135 TD
[(Standard)-2630.4(60)]TJ
/F6 1 Tf
9.8241 0 TD
(-)Tj
/F5 1 Tf
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[(1.55)-3628.5(2.67)]TJ
/F6 1 Tf
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(0.36)Tj
/F6 1 Tf
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[(1.44)-334.6(to)-336.1(0.72)-7429.1(0.66)-334.6(\(130\))-2630.9(0.51)]TJ
-28.7754 -1.3129 TD
[(Overall)-338.7(QoL)]TJ
1.002 -1.0135 TD
[(Coban)-335.3(2)-2742.1(6)0(9)-3186.5(1.01)-3628.5(1.53)]TJ
T*
[(Standard)-2630.4(61)-3186.5(1.14)-3628.5(1.99)-4261.9(0.13)]TJ
/F6 1 Tf
27.2264 0 TD
(-)Tj
/F5 1 Tf
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[(0.48)-334.6(to)-336.1(0.75)-7429.1(0.43)-334.6(\(128\))-2630.9(0.67)]TJ
ET
62.022 282.331 490.167 .28342 re
f
62.022 56.58 490.167 .22678 re
f
62.022 263.679 490.167 .22678 re
f
BT
/F9 1 Tf
9.845 0 0 9.845 97.3417 297.9779 Tm
(Table)Tj
/F5 1 Tf
3.0002 0 TD
(4.)Tj
/F9 1 Tf
1.2496 0 TD
[(Bandage)-336.6(Costs)-333.7(Between)]TJ
/F5 1 Tf
11.5401 0 TD
(0)Tj
/F9 1 Tf
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()Tj
/F5 1 Tf
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(10)Tj
/F9 1 Tf
1.3302 0 TD
(Days,)Tj
/F5 1 Tf
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(11)Tj
/F9 1 Tf
1.002 0 TD
()Tj
/F5 1 Tf
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(20)Tj
/F9 1 Tf
1.3302 0 TD
[(Days)-338.3(and)-332(in)-331.6(Total)-334(\(Values)-336.8(Are)-332(in)-337.3(Great)]TJ
-11.3443 -1.0135 TD
[(British)-331.7(Pounds\))-336.8(Uprated)-336.8(to)]TJ
/F5 1 Tf
12.9855 0 TD
(2021)Tj
/F9 1 Tf
2.3322 0 TD
(Costs)Tj
/F5 1 Tf
-23.276 -1.8427 TD
(N)Tj
/F7 1 Tf
3.4206 0 TD
[(Mean)-3328.8(SD)-3095.1(Difference)-2336.5(95%)-332.2(Condence)-335.9(interval)]TJ
/F5 1 Tf
30.0078 0 TD
(t)Tj
/F7 1 Tf
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[(\(df)-83.8(\))]TJ
/F5 1 Tf
6.0637 0 TD
(p)Tj
-48.1357 -1.8946 TD
[(Visits)-335.2(010)-332.2(days)]TJ
1.002 -1.0135 TD
[(Coban)-335.3(2)-3438.8(9)0(0)-3330.4(4.41)-3329(1.70)]TJ
/F6 1 Tf
21.5945 0 TD
(-)Tj
/F5 1 Tf
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(2.75)Tj
/F6 1 Tf
4.7969 0 TD
(-)Tj
/F5 1 Tf
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[(3.35)-328.8(to)]TJ
/F6 1 Tf
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(-)Tj
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[(2.15)-6409.8(9.10)-334.6(\(163\))]TJ
/F6 1 Tf
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/F5 1 Tf
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(0.001)Tj
-46.5348 -1.0135 TD
[(Standard)-3327.2(75)-3330.4(7.16)-3329(2.18)]TJ
-1.002 -1.3129 TD
[(Visits)-335.2(1120)-333.2(days)]TJ
1.002 -1.0135 TD
[(Coban)-335.3(2)-3438.8(9)0(0)-3330.4(1.96)-3329(2.01)-4100.7(0.97)-3046.9(0.35)-328.8(to)-336.2(1.58)-7515.5(3.11)-334.6(\(163\))-2878.5(0.002)]TJ
0 -1.0077 TD
[(Standard)-3327.2(75)-3330.4(0.99)-3329(1.97)]TJ
-1.002 -1.3187 TD
[(Total)-335.9(visits)]TJ
1.002 -1.0135 TD
[(Coban)-335.3(2)-3438.8(9)0(0)-3330.4(6.37)-3329(2.94)]TJ
/F6 1 Tf
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/F6 1 Tf
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/F5 1 Tf
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[(2.63)-328.8(to)]TJ
/F6 1 Tf
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[(0.94)-6409.8(4.15)-334.6(\(163\))]TJ
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-46.5348 -1.0077 TD
[(Standard)-3327.2(75)-3330.4(8.15)-3329(2.50)]TJ
-1.002 -1.3187 TD
[(Bandage)-339.7(costs)]TJ
1.002 -1.0135 TD
[(010)-332.2(days)]TJ
.9962 -1.0077 TD
[(Coban)-335.3(2)-2442.6(9)0(0)-2328.4(183.32)-2329(135.01)]TJ
/F6 1 Tf
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(38.50)Tj
/F6 1 Tf
5.2979 0 TD
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/F5 1 Tf
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[(87.54)-329.8(to)-336.2(10.55)-5961.7(1.55)-334.6(\(163\))-2878.5(0.12)]TJ
-26.5008 -1.0135 TD
[(Standard)-2331(75)-2328.4(221.82)-2329(183.50)]TJ
-.9962 -1.0135 TD
[(1120)-333.2(days)]TJ
.9962 -1.0077 TD
[(Coban)-335.3(2)-2442.6(9)0(0)-2829.4(88.78)-2829(92.39)-3600.7(61.26)-3047.8(36.71)-329.8(to)-336.2(85.81)-6514.5(4.92)-334.6(\(163\))]TJ
/F6 1 Tf
44.9857 0 TD
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-45.5386 -1.0135 TD
[(Standard)-2331(75)-2829.4(27.52)-2829(60.52)]TJ
-.9962 -1.0135 TD
(Total)Tj
.9962 -1.0135 TD
[(Coban)-335.3(2)-2442.6(9)0(0)-2328.4(272.10)-2329(195.39)-3601.6(22.76)]TJ
/F6 1 Tf
25.948 0 TD
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/F5 1 Tf
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[(38.38)-329.8(to)-336.2(83.90)-5961.7(0.74)-334.6(\(163\))-2878.5(0.46)]TJ
-26.5008 -1.0077 TD
[(Standard)-2331(75)-2328.4(249.34)-2329(201.18)]TJ
/F3 1 Tf
8.9663 0 0 8.9663 62.022 749.6502 Tm
(6)Tj
46.9476 0 TD
[(FRANKS)-337.3(ET)-338.7(AL.)]TJ
ET
endstream
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/F5 1 Tf
9.843 0 0 9.843 69.7323 479.792 Tm
0 0 0 rg
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[(This)-414.5(study)-420.1(was)-414.1(also)-420.2(undertaken)-417.8(to)-417(identify)-413.5(the)-419.3(costs)-415.3(of)]TJ
-1.0137 -1.1116 TD
[(treatment)-193.5(for)-187.5(an)-187.7(intensive)-191(phase)-191.9(of)-186.5(lymphedema)-189.9(management)]TJ
0 -1.1174 TD
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T*
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T*
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T*
[(emphasize)-470.8(the)-465.4(chronic)-465.1(nature)-464(and)-465.2(continuing)-467.6(care)-462.9(that)-466.6(is)]TJ
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T*
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T*
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T*
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T*
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[(32)-4.6(.7)-4.6(,)]TJ
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[(24)-4.6(.0)-4.6(,)]TJ
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T*
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(n)Tj
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(24)Tj
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T*
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T*
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T*
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T*
[(of)-241.9(tr)5.8(eat)5.6(ment)-242.1(epi)5.6(s).2(od)5.7(es)-241.7(var)5.8(i)-.1(es)-241.7(hu)5.7(gel)5.6(y)-247.7(with)-241.9(so)5.7(me)-243.1(cent)5.6(ers)-241.7(r)0(equi)5.6(red)]TJ
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T*
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T*
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